Regulatory Genomics, Epigenomics, and Proteomics
Image Credit: Sera Thornton and Laurie Boyer
Research in Regulatory Genomics, Epigenomics, and Proteomics at MIT deciphers the connections between the genetic blueprint and the resulting transcriptome and proteome, and between genome architecture and stably inherited phenotypes. Research groups utilize a wide range of methodologies, including machine learning, precision measurement, mathematical modeling, and network analysis.
Myriam Heiman
Sara Prescott
Li-Huei Tsai
Katie Galloway
Biologists glean insight into repetitive protein sequences
A computational analysis reveals that many repetitive sequences are shared across proteins and are similar in species from bacteria to humans.
MIT researchers used a technique called dot-plot matrix, which is a way to visually represent amino acid sequences, to compare protein sequences known as “low-complexity regions” across many different species.