Evolutionary and Computational Biology
Image Credit: Page Lab
Research in Evolutionary and Computational Biology leverages large-scale genomic, transcriptomic and related data across diverse species to unlock the molecular mechanisms of life.
CSB Thesis Defense
Student: Vincent Xue
Lab: Keating
Title: Modeling and Designing Bcl-2 Family Protein Interactions Using High-Throughput Interaction Data
Biologists' new peptide could fight many cancers
Drug that targets a key cancer protein could combat leukemia and other types of cancer.
MIT biologists have designed a new peptide that can disrupt a key protein that many types of cancers, including some forms of lymphoma, leukemia, and breast cancer, need to survive.
The new peptide targets a protein called Mcl-1, which helps cancer cells avoid the cellular suicide that is usually induced by DNA damage. By blocking Mcl-1, the peptide can force cancer cells to undergo programmed cell death.
CSB Thesis Defense
Student: Peter Freese
Lab: Burge
Title: "Biochemical and Functional Characterization of Human RNA Binding Proteins"